Our labs are located at the Douglas Mental Health University Institute, a research center in Montreal, Quebec. Since our increased practices to in vivo experiments, we have developed advanced analysis packages to register large and small neuronal circuits. Recording calcium activity with miniscope technology we are able to record neuronal activity in combination with optogenetics and electrophysiology in freely moving mice. Revealing the identity and activity patterns of neurons in the hippocampus and septum. The overarching goal is to understand the neuronal mechanisms underlying normal memory function in normal and in pathological conditions such as Alzheimer’s disease in mice models.

Sylvain Williams

Hippocampus and memory laboratory

Mark Brandon

Neurobiology of spatial memory in health and disease